ATS-13®

ADAMTS-13 Activity Assay

For the quantitative measurement of ADAMTS-13 protease activity

A large body of literature shows that ADAMTS-13 is the protease responsible for cleaving von Willebrand Factor. Significant decrease or absence of ADAMTS-13 activity has been demonstrated in the plasma of patients with thrombotic thrombocytopenic purpura (TTP). The lack of ADAMTS-13 activity results in the accumulation of multimers of von Willebrand Factor in the plasma and ultimately intravascular platelet aggregation resulting in the clinical symptoms associated with TTP. Mild or moderately decreased levels of ADAMTS-13 activity have also been associated with other disease states and conditions. Gen-Probe has developed a quantitative assay for the measurement of ADAMTS-13 protease activity in human plasma using FRET Technology.

Non-kinetic read
Quantitative
Length of assay (including dilutions) is less than 1 hour
Easy-to-use

Catalog No.	Description	Size	Avg Shelf Life	Storage
ATS-13	ATS-13® ADAMTS-13 Activity Assay	Maximum 40 Tests/Kit	12 months	Box A: -15 to -30°C
	ATS-13® ADAMTS-13 Activity Assay			Box B: 2 to 8°C

For Research Use Only.