A solid phase ELISA for the detection of IgG antibodies to donor-specific HLA Class I and HLA Class II antigens
MicroAMS® is designed to detect donor-specific HLA alloantibodies in transplant recipients that may lead to early graft loss or chronic rejection. Class I and Class II glycoproteins are solubilized from donor cells or tissue and captured using class-specific monoclonal antibodies which have been immobilized in the microwells. The recipient serum of interest is then added. A color change indicates the presence of donor-reactive antibodies.
- For detection of donor-specific HLA antibodies - Up to 44 tests against one donor for the presence of both Class I and Class II antibodies
- For detection of IgG antibodies
- No interference from antibodies to non-HLA glycoproteins
- Uses lysates (solubilized donor glycoproteins) that can be made from lymphocytes isolated from peripheral blood or cells from spleen
- New! Reduced volume requirement for both donor lysate and patient serum
- Lysates can be prepared in advance and stored for an extended period at -80°C
| Catalog No. | Description | Size | Avg Shelf Life | Storage |
|---|---|---|---|---|
| M-AMS | MicroAMS® - Class I & II | Maximum 44 Tests/Kit | 12 months | 2–8°C |
| LYMLB | Lymphocyte Lysis Buffer | 2.5mL | 2 Years | 2–8°C |
For In Vitro Diagnostic Use.